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The reason why is because the majority of growth hormone secretion happens during sleep, so if you're not getting adequate amounts, or not getting adequate slow-wave sleep, your growth hormone levels are going to suffer along with your ability to build and maintain muscle mass

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Based on available evidence, SCFAs exert protective effects by activating the Nrf2/GPX4 pathway to inhibit lipid peroxidation, while LPS acts through the dual mechanisms of suppressing the antioxidant defense system (GPX4) and disrupting iron metabolic homeostasis